The pancreas is a 15-centimeter-tall organ located in the back of the stomach and is connected to the duodenum. It secretes digestive enzymes of carbohydrates, proteins, and fats, and secretes insulin and glucagon to control blood sugar in the body.
What is pancreatic cancer?
Pancreatic cancer includes tumors that occur in endocrine cells that secrete hormones such as insulin, and is extremely small at 5% to 10%. More than 90% of tumors in exocrine cells related to digestive enzymes are commonly referred to as pancreatic cancer.
the cause of pancreatic cancer
The cause of pancreatic cancer is higher in men than in women, and in terms of blood type, the incidence rate is higher in the order of O type < A type < AB type < B type. It usually occurs in men over the age of 50, and the incidence rate is about 13 per 100,000 people. It is difficult to detect early because it is not possible to check in general medical checkups. The biggest cause is smoking, which accounts for 30%. Smokers are more than twice as likely to develop pancreatic cancer as non-smokers, and are risk factors for pancreatic cancer. High-calorie meals account for 20%. Obesity, a chronic disease of modern people, is caused by fatty meals and excessive meat intake, and obesity causes pancreatic cancer. Genetics accounts for 10% and chronic pancreatitis accounts for 4%. Pancreatitis refers to a disease in which the pancreatic glands are destroyed or local or overall inflammation occurs in the pancreas, and the cause is gallstones and alcohol. Symptoms of pancreatitis include pain in the pit of the stomach or on the left side of the body, and if temporary acute pancreatitis occurs frequently, it becomes chronic pancreatitis. Chronic pancreatitis is 10 to 16 times more likely to develop into pancreatic cancer, so be careful.
Symptom
Pancreatic cancer has no initial symptoms, so the early detection rate is very low at less than 10%. The first symptoms are pain and abdominal pain. Unexperienced pain such as pain in the left part of the body, back, chest or side, stomachache, etc. occurs. The second symptom is jaundice. Urine color turns red or black, or the whites of your eyes turn yellow. The third symptom is weight loss accompanied by indigestion and an unidentified appetite. If you lose more than 10% of your weight within 6 months, you should suspect it because it may be not only pancreatic cancer but also other cancers. The fourth symptom is when diabetes control is difficult. If you suddenly develop diabetes that you didn't have, or if your sugar level suddenly rises, you should suspect a cystic tumor of the pancreas. In the case of cystic tumors, some of them develop into cancer, so you need proper treatment.
Diagnostic and treatment methods
The diagnosis and treatment of pancreatic cancer is diagnosed by abdominal shear tomography (CT) or magnetic resonance imaging (MRI). If you are suspected of pancreatic cancer but are not found in magnetic resonance imaging, take a picture of the pancreas using endoscopes such as gastroscopy and endoscopic ultrasound and decide whether to operate. In addition, if the patient's condition is not good enough to perform surgery, important artery or vein involvement, liver or abdominal metastasis, and if chemotherapy and radiation are planned to reduce tumor size before resection, ultrasound-guided fine-grained treatment is used to plan treatment. In the first and second stages, there is no invasion of other organs and important arteries or veins, and in the case of resectable pancreatic cancer, auxiliary chemotherapy is performed after resection. In the case of borderline resection pancreatic cancer, chemotherapy is performed before resection. In the case of stage 3 and stage 4, it is the case of other organ invasion, important arteries, and veins. In the case of pancreatic cancer with remote metastasis confirmed, chemotherapy is performed, and in the case of locally advanced pancreatic cancer, radiation treatment can be performed after chemotherapy. Treatment anti-cancer drugs use polypyrrhine and gemcitabin + abracate. In the case of stage 3 and stage 4 and recurrent pancreatic cancer, these two anticancer drugs are alternately used. The amount and number of anticancer drugs administered are determined by the patient's condition and the degree of tumor invasion. In the 3rd and 4th stages, resection is not possible, but resection is performed by reducing the size of the tumor through chemotherapy. In the end, it is most important to detect it early after an accurate diagnosis, proceed with chemotherapy or surgery, and prevent recurrence and manage complications through chemotherapy. It is also important to quit smoking and reduce alcohol consumption and maintain a proper weight.
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